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Gene Helps Breast Cancer Spread
- By Cameron Inquiry
- Published 01/10/2009
- Breast Cancer Research
- Unrated
Cameron Inquiry
Cameron Inquiry is a resident of Newfoundland and Labrador who is somewhat outraged and disgusted at what has transpired in the Health Care System in Newfoundland and Labrador leading up to the revelation of the faulty hormone receptor tests and the impact that this scandal has had on the lives of the breast cancer patients and their families.
View all articles by Cameron InquiryResearchers have found a gene that makes breast cancer tumors more likely to resist treatments such as chemotherpay and more likely to spread to other organs. Terming this new gene as the "metastasis gene", researchers have found this in 30-40% of the breast cancer patients.
According to the researchers, when this gene is activated in breast cancer patients, it aids the breast cancer tumors to stick tightly to blood vessels in distant organs. As well, this gene encourages the cancer tumors to become resistent to chemotherapy drugs that have been traditionally used to treat breast cancer.
Researchers from both Princeton Universy and the Cancer Insitute of New Jersey reported their findings in the journal Cancer Cell.
The discovery of this gene could eventually lead to the development of
The new gene has been given the name Metadherin, or MTDH.
In examining this gene, researchers also found that it may play a role in prostate cancer metastases. The same genetic variant has been shown to be in approximately 20% of men suffering from prostate cancer.
Breast cancer is the leading cause of death in women, with the spreading of cancer and chemo-resistance being the two biggest challenges to curing breast cancer.
